NAD⁺ – Injectable Pen 500mg

£250.00

NAD⁺ (nicotinamide adenine dinucleotide) is an essential coenzyme present in all living cells, crucial for metabolic processes and proper cellular function.
It participates in oxidation-reduction reactions by alternating between the oxidized ( NAD⁺ ) and reduced ( NADH ) forms, enabling the transfer of electrons necessary for energy production and maintaining cellular homeostasis.

In addition to energy metabolism, NAD⁺ plays a key role in DNA repair and gene regulation through enzymes such as sirtuins and PARP, contributing to the protection of nerve cells, improved muscle function, and reduced aging processes.

Composition

  • Active ingredient: NAD⁺ (Nicotinamide Adenine Dinucleotide)
  • Concentration: 500 mg in 2 ml of solution
  • Equivalence: 50 mg corresponds to 20 units
  • Form: Ready-to-use, recombined and sterile solution

Notes

  • Product intended for research use only .
  • Not intended to diagnose, treat, or prevent any disease

NAD⁺ — Essential coenzyme for metabolism, longevity, and cellular function

NAD⁺ – Injectable Pen 500mg, NAD⁺ (nicotinamide adenine dinucleotide) is a universal coenzyme present in all living cells. It represents the oxidized form of NADH and plays a crucial role in electron transfer between biochemical reactions, supporting energy production and cellular homeostasis. Its primary function is to mediate redox reactions by switching between the oxidized and reduced forms of NAD⁺ , a cycle essential for ATP synthesis and the continuity of key metabolic pathways. In addition to energy metabolism, NAD⁺ participates in regulatory processes such as DNA repair, modulation of gene expression, and intracellular and extracellular communication.

Biochemical role and cellular pathways

NAD⁺ – Injectable Pen 500mg, is a cofactor in hundreds of enzymatic reactions. In mitochondrial bioenergetics, it supports glycolysis, the Krebs cycle, and the electron transport chain, serving as an electron acceptor/donor to maintain redox balance. In parallel, it acts as a substrate for sirtuins and PARP (poly-ADP-ribose polymerase), enzyme families that link metabolism to chromatin status, DNA damage repair, and stress response. Sirtuins, dependent on NAD⁺, are implicated in regulating gene expression, controlling inflammatory processes, and mitochondrial quality; PARP uses NAD⁺ to signal and orchestrate DNA repair, contributing to genomic stability.

NAD⁺ as an extracellular signal

In addition to its intracellular functions, NAD⁺ can be released into extracellular compartments in specific physiological contexts. Experimental evidence suggests that neurons in various regions (for example, in blood vessels, the bladder, the colon, and certain brain areas) release NAD⁺ as a signaling molecule . This additional dimension broadens our understanding of the coenzyme: it is not only an “energy transporter” but also a modulator of cell-to-cell communication, with potential implications for the regulation of smooth muscle tone and other peripheral functions.

Usage note and research context

The information provided here is for informational and educational purposes only and refers to primarily preclinical experimental evidence. This content does not constitute medical advice or indications for clinical use. Any uses of NAD⁺, its precursors, or combinations with other compounds remain the subject of research and scientific evaluation. Interpretation of the evidence must consider differences between species, doses, routes of administration, and experimental settings.

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